The name of this site reflects the fact that there are no effective medical therapies for secondary progressive multiple sclerosis. I’ve had MS now for a few years short of three decades and have been on the majority of the disease modifying MS therapies and tried a multitude of alternatives. I eat pretty healthy, but I can’t say that I follow the Terry Wahls Diet. I like to make my own herbal tinctures, think I sleep better on a grounding mat, and still get Ocrevus, even though I have my doubts it does much for SPMS. I’ve been reading studies on PubMed, MDPI, Nature and similar sites more so the past few years to see how to help fix SPMS myself and can see now why there is still no cure. However, to anyone newly diagnosed, if it were me, I would definitely get on an anti-CD20 B cell therapy. I am not a neurologist and these are just my interpretations on information I find online that can be somewhat fluid at times. I have also never done a blog before, but I opened my big mouth about it, so here goes.
This quote from a study I read sums up MS quite well. “MS pathogenesis is a complex process involving a vast array of cell types, that all vary in their phenotype and function, which can switch from pro- to anti-inflammatory and vice versa and thus their pathologic contribution, depends on the stage of disease, and other factors, including initial attack, damage extent, age, gut microbiome, environmental influences, genes, etc., and so on”.(1)
1– Negron A, Stüve O and Forsthuber TG (2020) Ectopic Lymphoid Follicles in Multiple Sclerosis: Centers for Disease Control? Front. Neurol. 11:607766. https://doi.org/10.3389/fneur.